Successful lead optimization employs integrated drug metabolism and pharmacokinetic (DMPK) screening strategies to:
- Drive successful drug discovery projects
- Identify preclinical proof of concept compounds
- Distinguish candidate molecules with excellent developability profiles Join this webinar to learn how compounds with good functional activity are evaluated in in vitro and in vivo DMPK studies, providing information on in vitro/in vivo correlations, mitigating potential risks, and informing the design and interpretation of PK/PD studies to demonstrate target engagement.
Key Learning Objectives:
- Learn how to develop an effective DMPK screening strategy
- Identify candidate molecules with favourable profiles
- Gain information on in vitro/in vivo correlations
- Learn how to identify preclinical proof of concept (POC) compounds
Register