Formulators are facing increasing pressure to reduce development time and cost. The need for controlled release formulations and complex oral solid dosage forms such as multilayer make their day-to-day life even more challenging.
Key to their success is to assess new tableting technology that will allow them to develop their formulation with scale-up and production in mind. Data generation is also critical to drive their decision-making process with confidence at every stage from early development to manufacturing.
With increasing interest in chronopharmaceutics, press-coated tablets have become a key technology in the field of modified release drug delivery systems. Although their benefits in terms of drug release have been largely studied, the understanding of the compaction process of press-coated tablets is yet to complete.
- How to increase your methodology and expertise when developing controlled release formulation
- How to accelerate formulation development, even for more complex tablet forms
- How to understand deeply the impact of geometrical process parameters on the press coating quality attributes
- How to benefit from a compaction simulator as a cost-effective tool to develop oral solid dosage forms
In this webinar, a joint experimental and numerical study from University of Bordeaux and Skyepharma’s research teams will be presented. The impact of process parameters such as ratios between the dimensions of the core and the dimensions of the whole tablet (thickness, diameter) will be demonstrated.
