The early drug development roadmap from discovery to preclinical IND and onwards can be challenging and difficult to navigate. Understanding each critical step, their timings, and potential risks at each stage requires extensive expertise. Collaborating with experienced service providers can help streamline this process, integrating all the necessary activities, removing potential hurdles, and allowing a seamless transition from discovery into clinical development.
Charles River & Quotient Sciences have formed a collaboration to accelerate the path to the clinic to better support customers. They have developed an integrated offering that seamlessly bridges molecules from early discovery to clinical proof-of-concept (POC) and beyond. Charles River’s deep expertise in medicinal chemistry, biology, DMPK, early pharmaceutics and non-clinical safety, coupled with Quotient Sciences’ expert knowledge of drug substance synthesis, drug product development & manufacturing and clinical testing services offer a solution under a single program of work. This tight integration of expertise and activities streamlines the outsourcing model, providing earlier and more informed decision-making, efficient technology transfer, and joint problem-solving.
In this presentation, senior leaders from Charles River and Quotient Sciences discuss how this collaboration helps customers by bringing expert knowledge, removing obstacles from the critical path, reducing development risks, and shortening the pathway to clinical development. Through case studies they will demonstrate how an integrated program provides customers with the full set of deliverables required to be “clinic ready”, and how this seamless transition between providers can improve the chances of clinical success.
Key topics covered include:
- The benefits of an integrated approach to accelerate to IND and beyond
- How this collaboration seamlessly delivers these integrated programs of work
- How technical transfers are achieved between organizations and how this can benefit clients in both time and cost saving
- A timeline overview for each stage of the development process
- Case studies that demonstrate the benefits of an integrated discovery to clinic approach
